乙烯副产C9燃料油萃取脱硫萃取剂

对C9燃料油溶剂萃取脱硫的萃取剂进行研究,选择①乙腈、②N-甲基吡咯烷酮(NMP)、③环丁砜与二甲基亚砜、④二乙二醇、三乙二醇和甲醇、乙醇、乙二醇⑤糠醛5组萃取剂对C9燃料油进行萃取实验,从中筛选出较佳的萃取剂.分别研究了含水量、油剂质量比对萃取脱硫率和收率的影响,确定适宜的萃取条件,为以后的工业化生产提供基础数据.在此基础上,考察不同萃取剂复配的脱硫效果.实验结果表明,含水10%~14%的乙腈溶液或含水15%~17%的NMP溶液是C9燃料油较为适宜的萃取溶剂,其与二乙二醇复配可以进一步提高脱硫效果.     

N-甲基葡萄糖胺的合成

通过多相催化氢化反应，以葡萄糖和甲胺为原料，兰尼镍为催化剂，制得了N-甲基葡萄糖胺，用正交实验确定了较佳工艺条件，收率达75．5％．     

萃取精馏系统中萃取剂变性结焦的原因探讨与防治

从萃取精馏系统的工艺流程、生产运行特点进行研究,分析了萃取精馏系统中萃取剂N甲基吡咯烷酮变性结焦的原因,提出了延缓萃取剂变性的方法,通过工艺改造实现了系统的充压保护。     

取向条件下N-甲基壳聚糖溶液浇铸膜中晶片聚集体的形成

用正交偏光显微镜观察取向了的硼(N-甲基壳聚糖)=30％的N-甲基壳聚糖／甲酸溶液浇铸膜中一种特殊的结晶形态．晶片呈圆形堆砌．其聚集体的直径为几十微米．晶片聚集体内晶片无规取向．但晶片聚集体整体沿剪切方向取向．扫描电镜和X光衍射实验证实了取向浇铸膜中晶片的这种堆砌方式．这种形态是先取向后结晶形成的．     

水溶液中六种氨基酸与两种酰胺的焓相互作用的研究

用2277热活性检测仪测定了310.15 K下,甘氨酸、L-丙氨酸、L-缬氨酸、L-丝氨酸、L-苏氨酸和L-脯氨酸6种α-氨基酸分别与N-甲基乙酰胺、N,N-二甲基乙酰胺分子在水溶液中的混合过程的焓变,根据McMillan-Mayer理论得到了各级焓对作用系数,并比较了各级焓对作用系数.结果表明,氨基酸与N,N-二甲基乙酰胺的焓对作用系数大于与N-甲基乙酰胺的焓对作用系数.由于N,N-二甲基乙酰胺中—CH3基团的增加,对丝氨酸的焓对作用系数改变较大.用溶质-溶质相互作用和溶质-溶剂相互作用理论对结果进行了解释.     

RESEARCH ON CONFORMATION OF CAPROLACTAM AND ITS ALKYL DERIVATIVES

Caprolactam is treated with dimethyl sulfate in benzene medium under conditions of various molar ratios to yield two different methylatcd products. The homogeneous reaction of caprolactam with dimethyl sulfate without any medium can only givc one methylated derivative. In a similar condition to that mentioned above, the reaction of caprolactam with diethylsulfate forms also one product, O-ethyl caprolactim. In this articlc NMR spectrum is applied to further identify the molecular structures of two methylated derivatives held by predecessors, and, applied the chemical shift reagent to induce the NMR and combined the field scanning and decoupling method to confirm the classification of signals, as a consequence the preferred conformation of caprolactam and its alkyl derivatives are proposed.     

Mechanism-based targeting of NMDA receptor functions

NMDA receptors (NRs) are key signaling proteins in the central nervous system and represent important targets for drug development in several neurologic disorders. They are critically involved with fundamental brain processes, and thus indiscriminate pharmacological suppression of NR currents has seen only modest therapeutic success so far. Targeting harmful NR receptor activities while sparing the receptor’s vital functions requires a better understanding of the complexity of NR activation reaction; of the range of mechanisms that modulate discrete receptor activities; and of the consequences of this modulation on specific receptor functions. A quantitative account of the NR activation pathway was recently proposed and validated. It describes the gating reaction as a sequential, multi-step process rather than a binary, on-off switch. Alongside isoform-specific modulators, state-specific modulators may represent sophisticated interventions with high potential for narrow, functional specifi city. Here I review physiologic mechanisms that control NR responses; the salient features of the NR activation reaction; and discuss the model’s validity and its implications for drug development and characterization.Submitted 25 May 2005; accepted 29 June 2005     

用于炼厂恶臭气体的液体脱硫剂研制

以甲基二乙醇胺为主剂,与适当的活化剂、促进剂等进行复配,筛选出了一种用于去除炼厂恶臭气体的安全、高效液体脱硫剂TL-MHC.考察了相关工艺参数如温度、气液比和恶臭气体中H2S含量对脱硫剂TL-MHC脱硫效果的影响,对脱硫剂TL-MHC的脱硫-再生机理进行了描述.实验结果表明:脱硫剂TL-MHC具有脱硫率高、再生利用率高和腐蚀性低等特点.     

己内酰胺与硫酸酯的反应研究

己内酰胺与硫酸二甲酯在不同的条件下反应生成两个同分异构体——O-甲基己内酰亚胺和N-甲基己内酰胺;己内酰胺与硫酸二乙酯在上述相似条件下只能得到O-乙基己内酰亚胺,此外,对上述己内酰亚胺的催化重排进行了研究。